Release rate and antimicrobial activity of gentamicin salts as coating for bone allografts

Release rate and antimicrobial activity of gentamicin salts as coating for bone allografts

antioxidant and antimicrobial activity of allium jesdianum extract

چکیده بررسی فعالیت ضد اکسیدانی و ضدمیکروبی عصاره گیاه بن سرخ (allium jesdianum) به کوشش: زهرا مقیمی هدف از این تحقیق بررسی میزان ترکیبات فنولی کل، ترکیبات فلاوونوئیدی کل، فعالیت ضداکسیدانی و ضدمیکروبی عصاره ی گیاه تازه و خشک بن سرخ بود. استخراج عصاره به روش های غوطه وری، استفاده از همزن مغناطیسی، دستگاه مایکروویو، امواج فراصوت و گرمادهی مقاومتی و با استفاده از متانول، اتانول و آب به عنوا...

Increased Release Time of Antibiotics from Bone Allografts through a Novel Biodegradable Coating

The use of bone allografts is contraindicated in septic revision surgery due to the high risk of graft reinfection. Antibiotic release from the graft may solve the problem and these combinations can theoretically be used for prevention or even therapy of infection. The present study investigated whether amoxicillin, ciprofloxacin, and vancomycin alone or in combination with chitosan or alginate...

Antimicrobial implants and bone allografts: new uses for old antibiotics

Bone grafting is the procedure whereby missing bone is replaced with material from either the patient’s own body (autograft), that of a donor (allograft) or with synthetics. The use of exogenous materials to reconstruct skeletal defects is not a new concept. Artificial, synthetic or natural substitutes, in the form of gold and silver plates and pieces of coconut shell, were found in cranial def...

Drug release and bone growth studies of antimicrobial peptide-loaded calcium phosphate coating on titanium.

Preventing infection is one of the major challenges in total hip and joint arthroplasty. The main concerns of local drug delivery as a solution have been the evolution of antibiotic-resistant bacteria and the potential inhibition of osseointegration caused by the delivery systems. This work investigated the in vitro drug release, antimicrobial performance, and cytotoxicity, as well as the in vi...